A massive clash on Monday Night Football as Chelsea welcome Manchester United to Stamford Bridge in the Premier League. United hammered Frank Lampard's side 4-0 in the reverse game.
Atletico Madrid host Liverpool in the Champions League Round of 16 at Wanda Metropolitano Stadium. Liverpool have always progressed against Spanish teams in a two-legged UCL tie.
Borussia Dortmund welcome former manager Thomas Tuchel and his PSG side to Signal Iduna Park for their UEFA Champions League Round of 16 first leg.
Tottenham host RB Leipzig in the first leg of their Champions League Round of 16 tie. The Tottenham Hotspur Stadium has seen more goals than any other venue in this season's UCL.
Atalanta face Valencia in the first leg of their UEFA Champions League Round of 16 tie at the San Siro. This will be the first ever encounter between the two sides.